Prenatal Exposure to the Great Chinese Famine and Risk of Intracerebral Hemorrhage in Mid-life: Prospective Cohort Study (P18-064-19)

The “Developmental Origins of Health and Disease” hypothesis suggests that adversity in early life, particularly in utero, affects health status later in life. We thus investigated whether prenatal exposure to the Great Chinese famine 1959–1961 was associated with risk of intracerebral hemorrhage (ICH) in adulthood. Included were 97,399 participants of the Kailuan Study, who were free of stroke, myocardial infarction, or cancer at baseline...