Chemerin inhibits vascular calcification through ChemR23 and is associated with lower coronary calcium in chronic kidney disease

Background Chemerin is an adipokine that signals through the G protein‐coupled receptor ChemR23 and is associated with inflammation, glucose homeostasis, lipid metabolism and renal function, all of which strongly influence cardiovascular risk. However, elevated chemerin provides a survival advantage in patients with chronic kidney disease ( CKD ), but how this relates to the cardiovascular phenotype is unknown. Objectives The aim of the present...