N6-(2-hydroxyethyl)-adenosine from Cordyceps cicadae attenuates hydrogen peroxide induced oxidative toxicity in PC12 cells

Volume: 34, Issue: 5, Pages: 1325 - 1334
Published: Jun 13, 2019
Abstract
N6-(2-hydroxyethyl)-adenosine (HEA), is one of the active molecule found in Cordyceps cicadae. The protective effect of HEA against H2O2 induced oxidative damage in PC12 cells and the mechanism of action was investigated. The cells were exposed to varying concentrations of HEA (5–40 μM) for a period of 24 h and further incubated with 100 μM of H2O2 for an another 12 h. Cell viability, LDH release, MMP collapse, Ca2+ overload, antioxidant...
Paper Details
Title
N6-(2-hydroxyethyl)-adenosine from Cordyceps cicadae attenuates hydrogen peroxide induced oxidative toxicity in PC12 cells
Published Date
Jun 13, 2019
Volume
34
Issue
5
Pages
1325 - 1334
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