Comparison of immune system development in nonclinical species and humans: Closing information gaps for immunotoxicity testing and human translatability
Abstract
• The developing immune system is uniquely sensitive to xenobiotic influence. • In vivo animal studies are important tools to understand immune system development. • There is an incomplete understanding of immune system development in nonclinical species. • Addressing this gap will improve study design and human translatability of in vivo...
Paper Details
Title
Comparison of immune system development in nonclinical species and humans: Closing information gaps for immunotoxicity testing and human translatability
Published Date
Oct 1, 2019
Journal
Volume
89
Pages
178 - 188
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