DNA Methylation and SNPs in VCX are Correlated with Sex Differences in the Response to Chronic Hepatitis B
Abstract
The study was conducted to explore the mechanisms of sex differences in the response to chronic hepatitis B (CHB) in terms of DNA methylation, SNP genotype, and gene expression. Genomic DNA was isolated from peripheral blood mononuclear cells (PBMCs) of CHB patients and healthy controls and evaluated using the Human Methylation 450 K Assay. The DNA methylation level at hg37 chromosome (CHR) X: 7810800 was further validated using pyrosequencing....
Paper Details
Title
DNA Methylation and SNPs in VCX are Correlated with Sex Differences in the Response to Chronic Hepatitis B
Published Date
Jun 3, 2019
Journal
Volume
34
Issue
5
Pages
489 - 500
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