Breakthrough Moments: Yoshiki Sasai’s Discoveries in the Third Dimension

Yoshiki Sasai pioneered the organoid field with his idea of mimicking embryonic development in 3D. We shine a spotlight on his seminal work describing how the innate ability of embryonic stem cells to self-organize into layers and grow in a polarized fashion fosters their appropriate differentiation and response to morphogens. Yoshiki Sasai pioneered the organoid field with his idea of mimicking embryonic development in 3D. We shine a spotlight...