Looking beyond PGC-1α: emerging regulators of exercise-induced skeletal muscle mitochondrial biogenesis and their activation by dietary compounds

Volume: 45, Issue: 1, Pages: 11 - 23
Published: Jan 1, 2020
Abstract
Despite its widespread acceptance as the “master regulator” of mitochondrial biogenesis (i.e., the expansion of the mitochondrial reticulum), peroxisome proliferator-activated receptor (PPAR) gamma coactivator-1 alpha (PGC-1α) appears to be dispensable for the training-induced augmentation of skeletal muscle mitochondrial content and respiratory function. In fact, a number of regulatory proteins have emerged as important players in skeletal...
Paper Details
Title
Looking beyond PGC-1α: emerging regulators of exercise-induced skeletal muscle mitochondrial biogenesis and their activation by dietary compounds
Published Date
Jan 1, 2020
Volume
45
Issue
1
Pages
11 - 23
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