Ripretinib turns off the switch in GIST
Abstract
Smith et al. report the design of ripretinib, an investigational tyrosine kinase inhibitor that forces the activation loop of KIT and PDGFRα into an inactive conformation and targets a broad spectrum of KIT and PDGFRα mutants in...
Paper Details
Title
Ripretinib turns off the switch in GIST
Published Date
Jun 7, 2019
Volume
18
Issue
7
Pages
499 - 499
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History