Mitochondrial fusion is required for regulation of mitochondrial DNA replication
Abstract
Mitochondrial dynamics is an essential physiological process controlling mitochondrial content mixing and mobility to ensure proper function and localization of mitochondria at intracellular sites of high-energy demand. Intriguingly, for yet unknown reasons, severe impairment of mitochondrial fusion drastically affects mtDNA copy number. To decipher the link between mitochondrial dynamics and mtDNA maintenance, we studied mouse embryonic...
Paper Details
Title
Mitochondrial fusion is required for regulation of mitochondrial DNA replication
Published Date
Jun 6, 2019
Journal
Volume
15
Issue
6
Pages
e1008085 - e1008085
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