Zebrafish Dscaml1 is Essential for Retinal Patterning and Function of Oculomotor Subcircuits

Pages: 658161
Published: Jun 3, 2019
Abstract
Down Syndrome Cell Adhesion Molecules (dscam and dscaml1) are essential regulators of neural circuit assembly, but their roles in vertebrate neural circuit function are still mostly unexplored. We investigated the role of dscaml1 in the zebrafish oculomotor system, where behavior, circuit function, and neuronal activity can be precisely quantified. Loss of zebrafish dscaml1 resulted in deficits in retinal patterning and light adaptation,...
Paper Details
Title
Zebrafish Dscaml1 is Essential for Retinal Patterning and Function of Oculomotor Subcircuits
Published Date
Jun 3, 2019
Journal
Pages
658161
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