Original paper
Leucine‐rich repeat kinase 2 regulates mouse dendritic cell migration by ORAI2
Abstract
The leucine-rich repeat kinase 2 (LRRK2) is expressed in various immune cells and involved in regulating inflammatory processes. LRRK2 facilitates calcium extrusion exchanger and sodium-calcium exchanger activity and hence influences intracellular Ca2+ concentration in dendritic cells (DCs). DC maturation and migration are governed by the intracellular Ca2+ concentration, but the related mechanisms whereby LRRK2 regulates DC function and...
Paper Details
Title
Leucine‐rich repeat kinase 2 regulates mouse dendritic cell migration by ORAI2
Published Date
Jun 5, 2019
Journal
Volume
33
Issue
9
Pages
9775 - 9784
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Notes
History