1734-P: A Considerable Mismatch of Measurements between Radioimmunoassay and Enzyme-Linked Immunosorbent Assay Tests for Anti-Glutamic Acid Decarboxylase Antibody

Most cases of type 1 diabetes mellitus are considered to be caused by pancreatic β-cell destruction through islet cell autoimmunity. Anti-glutamic acid decarboxylase antibody (GADA) is an important islet cell-associated autoantibody in the diagnosis of autoimmune type 1 diabetes mellitus. In Japan, the GADA assay kit was changed from radioimmunoassay (RIA) to enzyme-linked immunosorbent assay (ELISA) in 2015. Thereafter, a mismatch of...