358-OR: Adiponectin, Leptin, and FGF-21 Levels in Adolescents Exposed and Not Exposed to Gestational Diabetes—Results from the Danish National Birth Cohort

Background: Offspring of mothers with gestational diabetes mellitus (GDM) are at increased risk of developing metabolic diseases. Adipokines such as adiponectin and leptin may be involved in the underlying mechanisms. Fibroblast growth factor 21 (FGF-21) has recently been identified as a potent metabolic regulator. Therefore, we investigated the impact of fetal exposure to GDM on adiponectin, leptin and FGF-21 levels and their associations with...