Kidney cytosine methylation changes improve renal function decline estimation in patients with diabetic kidney disease
Abstract
Epigenetic changes might provide the biological explanation for the long-lasting impact of metabolic alterations of diabetic kidney disease development. Here we examined cytosine methylation of human kidney tubules using Illumina Infinium 450 K arrays from 91 subjects with and without diabetes and varying degrees of kidney disease using a cross-sectional design. We identify cytosine methylation changes associated with kidney structural damage...
Paper Details
Title
Kidney cytosine methylation changes improve renal function decline estimation in patients with diabetic kidney disease
Published Date
Jun 5, 2019
Journal
Volume
10
Issue
1
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