Original paper

Endogenous Na+, K+-ATPase inhibitors and CSF [Na+] contribute to migraine formation

Volume: 14, Issue: 6, Pages: e0218041 - e0218041
Published: Jun 7, 2019
Abstract
There is strong evidence that neuronal hyper-excitability underlies migraine, and may or may not be preceded by cortical spreading depression. However, the mechanisms for cortical spreading depression and/or migraine are not established. Previous studies reported that cerebrospinal fluid (CSF) [Na+] is higher during migraine, and that higher extracellular [Na+] leads to hyper-excitability. We raise the hypothesis that altered choroid plexus Na+,...
Paper Details
Title
Endogenous Na+, K+-ATPase inhibitors and CSF [Na+] contribute to migraine formation
Published Date
Jun 7, 2019
Journal
Volume
14
Issue
6
Pages
e0218041 - e0218041
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