Original paper
Synthesis, in vitro urease inhibitory potential and molecular docking study of Benzimidazole analogues
Abstract
Despite of many diverse biological activities exhibited by benzimidazole scaffold, it is rarely explored for the urease inhibitory potential. For that purpose, benzimidazole analogues 1-19 were synthesized and screened for in vitro urease inhibitory potential. Structures of all synthetic analogues were deduced by different spectroscopic techniques. All analogues revealed inhibition potential with IC50 values of 0.90 ± 0.01 to 35.20 ± 1.10 μM,...
Paper Details
Title
Synthesis, in vitro urease inhibitory potential and molecular docking study of Benzimidazole analogues
Published Date
Aug 1, 2019
Journal
Volume
89
Pages
103024 - 103024
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Notes
History