Overcoming hypoxia-induced chemoresistance to cisplatin through tumor oxygenation monitored by optical imaging
Abstract
Perfluorocarbon nanoparticles have been reported to deliver oxygen to tumors and reduce hypoxia-induced radioresistance, however few studies have been carried out to study its role in reducing hypoxia-induced chemoresistance. The oxygenation effect also varies dramatically between different perfluorocarbon formulations and protocols, and there have been no efficient tools to monitor dynamic changes of tumor oxygenation non-invasively. Our goal...
Paper Details
Title
Overcoming hypoxia-induced chemoresistance to cisplatin through tumor oxygenation monitored by optical imaging
Published Date
Jan 1, 2019
Journal
Volume
3
Issue
2
Pages
223 - 235
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