Paeonol prevents IL-1β-induced inflammatory response and degradation of type II collagen in human primary chondrocytes
Volume: 47, Issue: 1, Pages: 2139 - 2145
Published: May 30, 2019
Abstract
Osteoarthritis (OA) is a common joint disease for which a safe and reliable treatment has yet to be developed. Here, we demonstrated the potential benefit of treatment with paeonol, a derivative of Paeonia suffruticosa, in the treatment and prevention of OA. Chondrogenic cell line ATDC5 cells were cultured with IL-1β and the effects of paeonol were assessed through qRT-PCR, western blot analysis, MTT, ELISA, and NF-κB luciferase reporter gene...
Paper Details
Title
Paeonol prevents IL-1β-induced inflammatory response and degradation of type II collagen in human primary chondrocytes
Published Date
May 30, 2019
Volume
47
Issue
1
Pages
2139 - 2145
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