Visualization of spatiotemporal dynamics of human glioma stem cell invasion.
Abstract
Glioblastoma exhibits phenotypic and genetic heterogeneity, aggressive invasiveness, therapeutic resistance, and tumor recurrence, which can be explained by the existence of glioma stem cells (GSCs). In this study, we visualized the spatiotemporal dynamics of invasion of human GSCs in an orthotopic xenograft mouse model using time-lapse imaging of organotypic brain slice cultures and three-dimensional imaging of optically cleared whole brains....
Paper Details
Title
Visualization of spatiotemporal dynamics of human glioma stem cell invasion.
Published Date
May 6, 2019
Journal
Volume
12
Issue
1
Pages
45 - 45
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Notes
History