Solubilization of Carbamazepine in TPGS Micelles: Effect of Temperature and Electrolyte Addition
Abstract
d-α-Tocopheryl polyethylene glycol succinate (TPGS), a polyethylene glycol condensate, is a biologically important nonionic amphiphile. In this study, we report on aqueous solution behavior of TPGS with a focus on its clouding, surface activity, micellar characteristics, and solubilization capacity for a model hydrophobic drug, carbamazepine (CBZ). Micelles were characterized by dynamic light and small-angle neutron scattering studies as a...
Paper Details
Title
Solubilization of Carbamazepine in TPGS Micelles: Effect of Temperature and Electrolyte Addition
Published Date
May 28, 2019
Journal
Volume
20
Issue
5
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