Evaluation of anti-adipogenic active homoisoflavonoids from Portulaca oleracea

This study was performed to isolate antiobesity components from the crude extract of Portulaca oleracea . The crude extract was partitioned into n -hexane, 85% aqueous methanol, n -butanol, and water fractions. Their effects on adipogenic differentiation were evaluated in 3T3-L1 cells. Among the solvent fractions from P. olearacea , the 85% aq. MeOH effectively reduced the levels of lipid accumulation. Further purification of 85% aq. MeOH led to...