Safety of Proton Pump Inhibitors Based on a Large, Multi-Year, Randomized Trial of Patients Receiving Rivaroxaban or Aspirin

Volume: 157, Issue: 3, Pages: 682 - 691
Published: Sep 1, 2019
Abstract
Background & Aims null Proton pump inhibitors (PPIs) are effective at treating acid-related disorders. These drugs are well tolerated in the short term, but long-term treatment was associated with adverse events in observational studies. We aimed to confirm these findings in an adequately powered randomized trial. null Methods null We performed a 3 × 2 partial factorial double-blind trial of 17,598 participants with stable cardiovascular disease...
Paper Details
Title
Safety of Proton Pump Inhibitors Based on a Large, Multi-Year, Randomized Trial of Patients Receiving Rivaroxaban or Aspirin
Published Date
Sep 1, 2019
Volume
157
Issue
3
Pages
682 - 691
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