Original paper
Низкомолекулярные ингибиторы путей репарации двухцепочечных разрывов ДНК усиливают противовирусное действие системы CRISPR/Cas9 на моделях вируса гепатита B
Abstract
The CRISPR/Cas9 nuclease system can effectively suppress the replication of the hepatitis B virus (HBV), while covalently closed circular DNA (cccDNA), a highly resistant form of the virus, persists in the nuclei of infected cells. The most common outcome of DNA double-strand breaks (DSBs) in cccDNA caused by CRISPR/Cas9 is double-strand break repair by nonhomologous end-joining, which results in insertion/deletion mutations. Modulation of the...
Paper Details
Title
Низкомолекулярные ингибиторы путей репарации двухцепочечных разрывов ДНК усиливают противовирусное действие системы CRISPR/Cas9 на моделях вируса гепатита B
Published Date
Jan 1, 2019
Journal
Volume
53
Issue
2
Pages
311 - 323
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History