Synergism between fornix microstructure and beta amyloid accelerates memory decline in clinically normal older adults
Abstract
The fornix is the primary efferent white matter tract of the hippocampus and is implicated in episodic memory. In this study, we investigated whether baseline measures of altered fornix microstructure and elevated beta amyloid (Aβ) burden influence prospective cognitive decline. A secondary goal examined whether Aβ burden is negatively associated with fornix microstructure. 253 clinically normal older adults underwent diffusion-weighted imaging...
Paper Details
Title
Synergism between fornix microstructure and beta amyloid accelerates memory decline in clinically normal older adults
Published Date
Sep 1, 2019
Journal
Volume
81
Pages
38 - 46
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