Evolutionary transition between invertebrates and vertebrates via methylation reprogramming in embryogenesis
Abstract
Major evolutionary transitions are enigmas, and the most notable enigma is between invertebrates and vertebrates, with numerous spectacular innovations. To search for the molecular connections involved, we asked whether global epigenetic changes may offer a clue by surveying the inheritance and reprogramming of parental DNA methylation across metazoans. We focused on gametes and early embryos, where the methylomes are known to evolve divergently...
Paper Details
Title
Evolutionary transition between invertebrates and vertebrates via methylation reprogramming in embryogenesis
Published Date
May 24, 2019
Journal
Volume
6
Issue
5
Pages
993 - 1003
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History