Regional patterns of 18F-florbetaben uptake in presenilin 1 mutation carriers
Abstract
Individuals with autosomal dominant Alzheimer's disease (ADAD) present amyloid deposits before symptoms onset. We aimed to investigate efficacy and safety of 18F-florbetaben (FBB) for assessing amyloid deposition in ADAD. We acquired FBB positron emission tomography and magnetic resonance imaging of 25 individuals from PSEN1 families (NCT02362880). We studied individual uptake patterns, group differences, and correlation with estimated years to...
Paper Details
Title
Regional patterns of 18F-florbetaben uptake in presenilin 1 mutation carriers
Published Date
Sep 1, 2019
Journal
Volume
81
Pages
1 - 8
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