An overview of the molecular mechanisms underlying development and progression of bicuspid aortic valve disease

Volume: 132, Pages: 146 - 153
Published: Jul 1, 2019
Abstract
Bicuspid aortic valve (BAV) is a common congenital heart malformation frequently associated with the development of aortic valve diseases and severe aortopathy, such as aortic dilatation, aneurysm and dissection. To date, different genetic loci have been identified in syndromic and non- syndromic forms of BAV. Among these, genes involved in the regulation of extracellular matrix remodelling, epithelial to mesenchymal transition and nitric oxide...
Paper Details
Title
An overview of the molecular mechanisms underlying development and progression of bicuspid aortic valve disease
Published Date
Jul 1, 2019
Volume
132
Pages
146 - 153
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