Symptoms of Major Depressive Disorder Scale: Performance of a Novel Patient-Reported Symptom Measure

BackgroundThe Symptoms of Major Depressive Disorder Scale (SMDDS) was expressly developed on the basis of qualitative data to directly incorporate patients' voices into evaluation of treatment benefit in major depressive disorder (MDD) clinical trials.ObjectivesTo collect quantitative data necessary to refine/optimize the SMDDS and document its psychometric properties.MethodsIn this multicenter, observational study, participants with clinically...