In vitro effects of the activity of novel platinum (II) complex in canine and human cell lines

Volume: 17, Issue: 4, Pages: 497 - 506
Published: Jun 20, 2019
Abstract
The anticancer activity of novel platinum derivative, a complex of platinum with tris(2‐carboxyethyl)phosphine (Pt‐TCEP), has been evaluated in canine (D‐17) and human osteosarcoma (U2‐OS) cell lines. Viability of cells after incubation for 24 or 72 hours with increasing concentrations (0.625, 1.25, 2.50, 5, 10 and 20 μM) of Pt‐TCEP was tested in an MTT assay and compared to effect of cisplatin. Longer‐term effect of Pt‐TCEP was evaluated in the...
Paper Details
Title
In vitro effects of the activity of novel platinum (II) complex in canine and human cell lines
Published Date
Jun 20, 2019
Volume
17
Issue
4
Pages
497 - 506
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