A core genome approach that enables prospective and dynamic monitoring of infectious outbreaks
Abstract
Whole-genome sequencing is increasingly adopted in clinical settings to identify pathogen transmissions, though largely as a retrospective tool. Prospective monitoring, in which samples are continuously added and compared to previous samples, can generate more actionable information. To enable prospective pathogen comparison, genomic relatedness metrics based on single-nucleotide differences must be consistent across time, efficient to compute...
Paper Details
Title
A core genome approach that enables prospective and dynamic monitoring of infectious outbreaks
Published Date
May 24, 2019
Journal
Volume
9
Issue
1
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