A genome‐wide association study‐derived polygenic score for interleukin‐1β is associated with hippocampal volume in two samples
Abstract
Accumulating research suggests that the pro‐inflammatory cytokine interleukin‐1β (IL‐1β) has a modulatory effect on the hippocampus, a brain structure important for learning and memory as well as linked with both psychiatric and neurodegenerative disorders. Here, we used an imaging genetics strategy to test an association between an IL‐1β polygenic score and hippocampal volume in two independent samples. Our polygenic score was derived using...
Paper Details
Title
A genome‐wide association study‐derived polygenic score for interleukin‐1β is associated with hippocampal volume in two samples
Published Date
May 22, 2019
Journal
Volume
40
Issue
13
Pages
3910 - 3917
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