An update on genetic frontotemporal dementia.
Abstract
Frontotemporal dementia (FTD) is a highly heritable group of neurodegenerative disorders, with around 30% of patients having a strong family history. The majority of that heritability is accounted for by autosomal dominant mutations in the chromosome 9 open reading frame 72 (C9orf72), progranulin (GRN), and microtubule-associated protein tau (MAPT) genes, with mutations more rarely seen in a number of other genes. This review will discuss the...
Paper Details
Title
An update on genetic frontotemporal dementia.
Published Date
May 22, 2019
Journal
Volume
266
Issue
8
Pages
2075 - 2086
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