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doi.org/10.1016/j.biopsych.2019.03.630

F93. CYP2D6 Revisited in GENDEP, a Multicenter Clinical Trial of Nortriptyline and Escitalopram

..., Peter McGuffin
98
Biological Psychiatry10.60
Volume: 85, Issue: 10, Pages: S248 - S249
Published: May 1, 2019
Abstract
The polymorphic CYP2D6 enzyme is estimated to be responsible for the oxidation of 20-25% of all drugs in clinical use. However, genotyping for its variants is not routinely clinically available. The gene is particularly complex, with different platforms analysing different subsets of variants. GENDEP (Genome-based therapeutic drugs for depression) is a multicentre clinical trial which found an association between CYP2D6 genotype and...
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Paper Details
Title
F93. CYP2D6 Revisited in GENDEP, a Multicenter Clinical Trial of Nortriptyline and Escitalopram
DOI
doi.org/10.1016/j.biopsych.2019.03.630
Published Date
May 1, 2019
Journal
Biological Psychiatry
Volume
85
Issue
10
Pages
S248 - S249
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