Profiling of Epigenetic Features in Clinical Samples Reveals Novel Widespread Changes in Cancer
Abstract
Aberrations in histone post-translational modifications (PTMs), as well as in the histone modifying enzymes (HMEs) that catalyze their deposition and removal, have been reported in many tumors and many epigenetic inhibitors are currently under investigation for cancer treatment. Therefore, profiling epigenetic features in cancer could have important implications for the discovery of both biomarkers for patient stratification and novel epigenetic...
Paper Details
Title
Profiling of Epigenetic Features in Clinical Samples Reveals Novel Widespread Changes in Cancer
Published Date
May 24, 2019
Journal
Volume
11
Issue
5
Pages
723 - 723
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