Long-term evolution of CD4+ cell count in patients under combined antiretroviral therapy

Combined antiretroviral treatment (cART) results in profound immunologic improvement, but it is unclear whether CD4 cell counts return to levels similar to those of HIV-negative individuals. We explore long-term CD4 cell count evolution post-cART and its association with baseline levels, virologic suppression, pre-cART cumulative viremia and other factors.Data were derived from the AMACS. Included individuals were adults who started cART, at...