Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data.
Abstract
Dental caries and periodontitis account for a vast burden of morbidity and healthcare spending, yet their genetic basis remains largely uncharacterized. Here, we identify self-reported dental disease proxies which have similar underlying genetic contributions to clinical disease measures and then combine these in a genome-wide association study meta-analysis, identifying 47 novel and conditionally-independent risk loci for dental caries. We show...
Paper Details
Title
Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data.
Published Date
Jun 24, 2019
Journal
Volume
10
Issue
1
Pages
2773 - 2773
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Notes
History