Immunometabolism orchestrates training of innate immunity in atherosclerosis

Volume: 115, Issue: 9, Pages: 1416 - 1424
Published: May 3, 2019
Abstract
Atherosclerosis is characterized by a persistent, low-grade inflammation of the arterial wall. Monocytes and monocyte-derived macrophages play a pivotal role in the various stages of atherosclerosis. In the past few years, metabolic reprogramming has been identified as an important controller of myeloid cell activation status. In addition, metabolic and epigenetic reprogramming are key regulatory mechanisms of trained immunity, which denotes the...
Paper Details
Title
Immunometabolism orchestrates training of innate immunity in atherosclerosis
Published Date
May 3, 2019
Volume
115
Issue
9
Pages
1416 - 1424
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