Persistent changes in liver methylation and microbiome composition following reversal of diet-induced non-alcoholic-fatty liver disease

Volume: 76, Issue: 21, Pages: 4341 - 4354
Published: May 22, 2019
Abstract
Non-alcoholic fatty liver disease (NAFLD) is a metabolic liver disease that is thought to be reversible by changing the diet. To examine the impact of dietary changes on progression and cure of NAFLD, we fed mice a high-fat diet (HFD) or high-fructose diet (HFrD) for 9 weeks, followed by an additional 9 weeks, where mice were given normal chow diet. As predicted, the diet-induced NAFLD elicited changes in glucose tolerance, serum cholesterol,...
Paper Details
Title
Persistent changes in liver methylation and microbiome composition following reversal of diet-induced non-alcoholic-fatty liver disease
Published Date
May 22, 2019
Volume
76
Issue
21
Pages
4341 - 4354
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