Two transcription factors cooperatively regulate DHN melanin biosynthesis and development in Pestalotiopsis fici

Summary Fungal 1,8‐dihydroxynaphthalene (DHN) melanin plays important roles in UV protection, oxidative stress and pathogenesis. However, knowledge of the regulatory mechanisms of its biosynthesis is limited. Previous studies showed two transcription factors, PfmaF and PfmaH, located in the DHN melanin biosynthetic gene cluster ( Pfma ) in Pestalotiopsis fici . In this study, deletion of PfmaH resulted in loss of melanin and affected conidia...