F148. 301 Cognitive Loci Identified in Large-Scale GWAS Meta-Analysis

Two recent large-scale GWAS have amassed sample sizes in excess of 300,000 individuals for genomic discovery of general cognitive ability (Davies et al. 2018; Savage et al. 2018). Here, we extend these efforts using meta-analytic approaches, accounting for sample overlap, to identify novel variants and genes associated with cognitive...