Placental trophoblast transfer of opioids following exposures to individual or mixtures of opioids in vitro

Volume: 244, Issue: 10, Pages: 846 - 849
Published: May 15, 2019
Abstract
Infants born with neonatal abstinence syndrome increased 5-fold between 2000 and 2012. Prenatal exposure to opioids has been linked to altered brain development, congenital heart defects, neural tube defects, and clubfoot. In the study presented here, placental transfer rate of six opioids; morphine, heroin, fentanyl, methadone, oxycodone, and naloxone was compared in vitro using a human trophoblast cell monolayer model, BeWo b30. The rate and...
Paper Details
Title
Placental trophoblast transfer of opioids following exposures to individual or mixtures of opioids in vitro
Published Date
May 15, 2019
Volume
244
Issue
10
Pages
846 - 849
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