Novel multi-targeted inhibitors suppress ocular neovascularization by regulating unique gene sets
Abstract
Neovascular diseases, such as many cancers and ocular disorders, are life threatening and devastating. Although anti-vascular endothelial growth factor A (VEGF-A) therapy is available, many patients are not responsive and drug resistance can develop. To try to overcome these problems, combination therapy targeting VEGF-A and platelet-derived growth factor B (PDGF-B) was tested. However, one obvious drawback was that the other VEGF and PDGF...
Paper Details
Title
Novel multi-targeted inhibitors suppress ocular neovascularization by regulating unique gene sets
Published Date
Aug 1, 2019
Journal
Volume
146
Pages
104277 - 104277
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