Rapamycin modulates tissue aging and lifespan independently of the gut microbiota in Drosophila
Abstract
The FDA approved drug rapamycin can prolong lifespan in diverse species and delay the onset of age-related disease in mammals. However, a number of fundamental questions remain unanswered regarding the mechanisms by which rapamycin modulates age-related pathophysiology and lifespan. Alterations in the gut microbiota can impact host physiology, metabolism and lifespan. While recent studies have shown that rapamycin treatment alters the gut...
Paper Details
Title
Rapamycin modulates tissue aging and lifespan independently of the gut microbiota in Drosophila
Published Date
May 24, 2019
Journal
Volume
9
Issue
1
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