Isl1-expressing non-venous cell lineage contributes to cardiac lymphatic vessel development
Abstract
The origin of the mammalian lymphatic vasculature has been studied for more than a century; however, details regarding organ-specific lymphatic development remain unknown. A recent study reported that cardiac lymphatic endothelial cells (LECs) stem from venous and non-venous origins in mice. Here, we identified Isl1-expressing progenitors as a potential non-venous origin of cardiac LECs. Genetic lineage tracing with Isl1-Cre reporter mice...
Paper Details
Title
Isl1-expressing non-venous cell lineage contributes to cardiac lymphatic vessel development
Published Date
Aug 1, 2019
Journal
Volume
452
Issue
2
Pages
134 - 143
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