RNA Packaging in HIV
Abstract
Highly selective packaging of HIV-1 RNA into virus particles is required for successful virus replication. However, cellular RNAs can also be packaged under some conditions. Thus, in infected cells, viral RNA is competing with an excess of cellular RNA for incorporation into assembling particles. Viral RNA can fold into two alternative conformers. Only one of these can dimerize, as required for packaging into virus particles. Virus particles are...
Paper Details
Title
RNA Packaging in HIV
Published Date
Aug 1, 2019
Journal
Volume
27
Issue
8
Pages
715 - 723
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