Non-Uniformity of Projection Distributions Attenuates Resolution in Cryo-EM

Pages: 635938
Published: May 13, 2019
Abstract
null Virtually every single-particle cryo-EM experiment currently suffers from specimen adherence to the air-water interface, leading to a non-uniform distribution in the set of projection views. Whereas it is well accepted that uniform projection distributions can lead to high-resolution reconstructions, non-uniform (anisotropic) distributions can negatively affect map quality, elongate structural features, and in some cases, prohibit...
Paper Details
Title
Non-Uniformity of Projection Distributions Attenuates Resolution in Cryo-EM
Published Date
May 13, 2019
Journal
Pages
635938
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