Abstract P1-06-08: A p53-independent DNA damage response that regulates breast cancer phenotypes

Volume: 79
Published: Feb 15, 2019
Abstract
Defects in the DNA damage repair system result in increased genomic instability and have recently been implicated as being drivers of tumorigenesis in both familial and sporadic breast cancers. To maintain genomic integrity, cells have a DNA damage response (DDR) mechanism that functions to repair damaged DNA efficiently and commits cells to death if damage is irreparable. Failure of this mechanism results in genomic instability and cancer...
Paper Details
Title
Abstract P1-06-08: A p53-independent DNA damage response that regulates breast cancer phenotypes
Published Date
Feb 15, 2019
Volume
79
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