The role of hedonics in the Human Affectome

Published on Jul 1, 2019in Neuroscience & Biobehavioral Reviews8.00
· DOI :10.1016/j.neubiorev.2019.05.003
Susanne Becker11
Estimated H-index: 11
Anne-Kathrin Bräscher6
Estimated H-index: 6
+ 16 AuthorsYi Wang18
Estimated H-index: 18
Experiencing pleasure and displeasure is a fundamental part of life. Hedonics guide behavior, affect decision-making, induce learning, and much more. As the positive and negative valence of feelings, hedonics are core processes that accompany emotion, motivation, and bodily states. Here, the affective neuroscience of pleasure and displeasure that has largely focused on the investigation of reward and pain processing, is reviewed. We describe the neurobiological systems of hedonics and factors that modulate hedonic experiences (e.g., cognition, learning, sensory input). Further, we review maladaptive and adaptive pleasure and displeasure functions in mental disorders and well-being, as well as the experience of aesthetics. As a centerpiece of the Human Affectome Project, language used to express pleasure and displeasure was also analyzed, and showed that most of these analyzed words overlap with expressions of emotions, actions, and bodily states. Our review shows that hedonics are typically investigated as processes that accompany other functions, but the mechanisms of hedonics (as core processes) have not been fully elucidated.
  • References (345)
  • Citations (0)
Published on Apr 1, 2019in Pain6.03
Edita Navratilova20
Estimated H-index: 20
Guangchen Ji18
Estimated H-index: 18
+ 5 AuthorsFrank Porreca F94
Estimated H-index: 94
AbstractChronic pain is associated with neuroplastic changes in the amygdala that may promote hyper-responsiveness to mechanical and thermal stimuli (allodynia and hyperalgesia) and/or enhance emotional and affective consequences of pain. Stress promotes dynorphin-mediated signaling at the kappa opi
Published on Apr 1, 2019in Nature Reviews Neuroscience33.16
Kent C. Berridge81
Estimated H-index: 81
(UM: University of Michigan)
How do brain systems evaluate the affective valence of a stimulus — that is, its quality of being good or bad? One possibility is that a neural subsystem, or ‘module’ (such as a subregion of the brain, a projection pathway, a neuronal population or an individual neuron), is permanently dedicated to mediate only one affective function, or at least only one specific valence — an idea that is termed here the ‘affective modules’ hypothesis. An alternative possibility is that a given neural module ca...
Published on Jan 14, 2019in Schizophrenia Bulletin7.29
Gregory P. Strauss33
Estimated H-index: 33
(UGA: University of Georgia),
Farnaz Zamani Esfahlani1
Estimated H-index: 1
(Binghamton University)
+ 4 AuthorsHiroki Sayama24
Estimated H-index: 24
(Binghamton University)
Published on Jan 2, 2019in Cognition & Emotion2.37
Eddie Harmon-Jones63
Estimated H-index: 63
(UNSW: University of New South Wales)
ABSTRACTThe field of cognition and emotion has grown considerably over the past 30 years, with an increased emphasis on the relationships between emotional and motivational components and how they contribute to basic perceptual, cognitive, and neural processes. For instance, research has revealed that emotion often influences these processes via emotion’s relationship with motivational dimensions, as when positive emotions low versus high in approach motivational intensity have different influen...
Published on Dec 1, 2018in Journal of Neurodevelopmental Disorders3.59
Keri S. Rosch10
Estimated H-index: 10
(ICSCI: Kennedy Krieger Institute),
Stewart H. Mostofsky58
Estimated H-index: 58
(ICSCI: Kennedy Krieger Institute),
Mary Beth Nebel19
Estimated H-index: 19
(ICSCI: Kennedy Krieger Institute)
Background Attention-deficit/hyperactivity disorder (ADHD) is associated with atypical fronto-subcortical neural circuitry and heightened delay discounting, or a stronger preference for smaller, immediate rewards over larger, delayed rewards. Recent evidence of ADHD-related sex differences in brain structure and function suggests anomalies in fronto-subcortical circuitry may differ among girls and boys with ADHD. The current study examined whether the functional connectivity (FC) within fronto-s...
Annekathrin Schacht26
Estimated H-index: 26
(GAU: University of Göttingen),
Pascal Vrti13
Estimated H-index: 13
(MPG: Max Planck Society)
Social information is particularly relevant for the human species because of its direct link to guiding physiological responses and behavior. Accordingly, extant functional magnetic resonance imaging (fMRI) data suggest that social content may form a unique stimulus dimension. It remains largely unknown, however, how neural activity underlying social (versus nonsocial) information processing temporally unfolds, and how such social information appraisal may interact with the processing of other s...
Published on Dec 1, 2018in Scientific Reports4.01
Yu Fu3
Estimated H-index: 3
(Cornell University),
Emre Selcuk10
Estimated H-index: 10
(METU: Middle East Technical University)
+ 1 AuthorsRichard A. Depue29
Estimated H-index: 29
(Cornell University)
Soft touch possesses strong prosocial effects that facilitate social bonding and group cohesion in animals. Touch activates opioids (OP) and oxytocin (OXT), two neuromodulators involved in affiliative behaviors and social bonding. We examined whether touch serves as an unconditioned reward in affective conditioning of human faces, a basic process in social bonding, and whether this process is mediated by variation in mu-OP (OPRM1) and OXT (rs53576) receptor genes. Participants viewed affectively...
Published on Dec 1, 2018in Scientific Reports4.01
Louise Urien2
Estimated H-index: 2
(NYU: New York University),
Zhengdong Xiao2
Estimated H-index: 2
(NYU: New York University)
+ 3 AuthorsJing Wang11
Estimated H-index: 11
(NYU: New York University)
Pain is a complex sensory and affective experience. Through its anticipation, animals can learn to avoid pain. Much is known about passive avoidance during a painful event; however, less is known about active pain avoidance. The anterior cingulate cortex (ACC) is a critical hub for affective pain processing. However, there is currently no mechanism that links ACC activities at the cellular level with behavioral anticipation or avoidance. Here we asked whether distinct populations of neurons in t...
Published on Nov 1, 2018in Psychiatry Research-neuroimaging2.21
Julie Walsh-Messinger7
Estimated H-index: 7
(Wright State University),
Philip S. Wong7
Estimated H-index: 7
(LIU: Long Island University)
+ 4 AuthorsDolores Malaspina45
Estimated H-index: 45
(ISMMS: Icahn School of Medicine at Mount Sinai)
Abstract The neurocircuitries subserving affective and olfactory processes overlap, are sexually dimorphic, and show disruptions in schizophrenia, suggesting their intersection may be a window on the core process producing psychosis. This study investigated diagnostic and sex differences in hedonic judgments of odors and smell identification in 26 schizophrenia cases and 27 healthy controls. Associations between olfaction measures and psychiatric symptoms were also examined. Cases and controls h...
Published on Oct 1, 2018in Current opinion in behavioral sciences
Jeffrey S. Mogil73
Estimated H-index: 73
(McGill University)
Whether there are sex differences in pain sensitivity is a topic of enduring interest. This question has essentially been answered, with a clear consensus emerging in the direction of the difference in humans. More importantly, though, there is also much evidence for robust qualitative differences in pain mechanisms between the sexes, in both rodents and humans, predictive of the eventual sex-specific treatment of pain. This review details some of the known differences in pain circuitry between ...
Cited By0