Original paper
HPV16 E6/E7 expression in circulating tumor cells in oropharyngeal squamous cell cancers: A pilot study
Abstract
Objectives Human papillomavirus-related oropharyngeal squamous cell carcinoma (HPV+ OPSCC) is increasing in incidence. Although HPV+ OPSCC has favorable prognosis, 10 to 25% of HPV+ OPSCCs eventually recur. We sought to evaluate the feasibility of detection of HPV16 E6/E7 expression in Circulating Tumor Cells (CTCs) and its utility as a prognostic tool in HPV16-associated OPSCC. Materials and methods We developed a highly sensitive RT-qPCR assay...
Paper Details
Title
HPV16 E6/E7 expression in circulating tumor cells in oropharyngeal squamous cell cancers: A pilot study
Published Date
May 9, 2019
Journal
Volume
14
Issue
5
Pages
e0215984 - e0215984
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Notes
History