The Role of Reactive Oxygen Species in In Vitro Cardiac Maturation
Abstract
Recent advances in developmental biology and biomedical engineering have significantly improved the efficiency and purity of cardiomyocytes (CMs) generated from pluripotent stem cells (PSCs). Regardless of the protocol used to derive CMs, these cells exhibit hallmarks of functional immaturity. In this Opinion, we focus on reactive oxygen species (ROS), signaling molecules that can potentially modulate cardiac maturation. We outline how ROS...
Paper Details
Title
The Role of Reactive Oxygen Species in In Vitro Cardiac Maturation
Published Date
Jun 1, 2019
Journal
Volume
25
Issue
6
Pages
482 - 493
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